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Canadian Energy Companies Benefiting From Global Turbulence
The world is going through a lot of chaos right now. From a war in Ukraine to a looming recession back home, people are struggling to live as normal. But through this all, the biggest Canadian energy stocks are getting stronger. Why is this and should you invest?
Before getting into the specifics of the stock market and why commodities are benefiting, it is important to go through every global event that is having a major impact.
The glut of global turbulence
Russia’s Invasion of Ukraine
To start with, Russia’s invasion of Ukraine is the most obvious factor in global turbulence at the moment. The world was not ready to deal with such an invasion. Negotiations were expected to keep Russia from choosing this approach, considering what they would have to lose. Massive sanctions would cripple Russia’s economy, and a war would not seem worth it.
However, they went ahead and global sanctions went into place. Unfortunately, these sanctions do not only affect Russia. Rather, they impact just about every other country as well. Russia bears the biggest brunt, but without the resources they provide to other
countries, the world is struggling to cope.
This is hurting developing countries more than any other, as they do not have the resources to spend on low supplies of energy in high demand. Locals are paying the price, with costs rising dramatically. However, developed nations are struggling as well, including the US and Canada. We’re seeing record high inflation that is making life difficult for everyone. We may face shortages if this war continues for much longer.
China’s COVID Lockdowns
While it has started to feel like COVID is finally over, China has been implementing new lockdowns to control another wave. This has led to a low supply of goods coming from China, impacting trade around the world at a time in which supply of almost every
commodity is low.
It’s not just the lack of production on Chinese shores that is impacting the rest of the world. The reality they are going through is causing a lot of unease. The pandemic started there, after all, and their inability to contain it led to the events of the past two and a half years. Fears that they will trigger a new wave with disastrous consequences are not unfounded.
Supply-chain issues caused by the pandemic around the world have still not returned to normal. If lockdowns go into place globally, these issues will get worse once again and it will be even more difficult to recover.
Global Recession
The threat of a global recession that rivals the Great Recession is looming over us. In the US, out-of-control inflation in spite of high interest rates, along with highly overvalued properties, are driving fears.
Whether a recession will occur and how bad it will be is impossible to determine at this point. But the potential is causing people to make decisions with huge financial consequences. This leaves us all the more at risk of chaos.
In this context, why are the biggest Canadian energy companies benefiting? What does this mean for stock traders?
Energy is in high demand
The above events have all impacted the supply of many commodities. Whether it is due to sanctions or lockdowns in China, it is becoming extremely difficult to get hold of just about any consumables. However, there is nothing in higher demand than energy.
Energy is by far Russia’s biggest export. Russia is also one of the biggest exporters of energy in the world, especially when it comes to crude oil. For this reason, sanctions are not all-encompassing. Many European countries simply cannot function without importing Russian energy.
The same is not true for the US, who have been able to cut off all energy imports from Russia. But it is still not comfortable, and all kinds of energy are in high demand.
This is particularly good for the biggest Canadian energy companies. One of the reasons the US can survive without importing Russian energy is due to the supply of energy from Canada. With such high demand, and supply that is limited to an extent, the price of
Canadian energy has risen rapidly.
The strength of the US dollar
With all of that being said, you may be wondering why Canadian energy companies are benefiting so much while US companies are not having as much luck. This has a lot to do with the strength of the US dollar.
The US dollar is considered a safe haven currency. It tends to stay strong regardless of what is happening in the world. This becomes a self-fulfilling property, as currency traders flock to buy US dollars in times of trouble, causing it to strengthen in spite of economic downturns.
China’s difficulties also boost the US currency, as traders turn to the US to import goods unavailable during China’s lockdowns.
The strength of the US dollar is, at least in the short term, great for Canadian energy companies. With demand for their energy in the US higher than ever, they are receiving US dollars that are particularly strong and have more buying power in Canada. The biggest Canadian energy companies are therefore flying higher than their US counterparts, who are earning the same dollars which, due to high inflation, have lower buying power than before.
Of course, this is a double-edged sword. Right now, the strength of the US dollar is great for Canadian energy companies. But over time it will start to impact the cost of all imports from the US, increasing the expenses these companies face and cancelling out any benefits.
Should you invest in Canadian energy stocks?
Bringing this back to the buying and selling of commodities on the stock market, is this the perfect time to invest in the biggest Canadian energy stocks? While it may seem so, the answer is a little more complicated than you might think.
The problem with the current strength of Canadian energy companies is that it is caused by factors that are supposed to be temporary. Sanctions on Russia are not meant as a punishment for their crimes. Rather, they are in place to put pressure on Russia to end the war before their economy collapses and they are bereft of necessary resources.
It is either that or the rest of the world capitulates due to an inability to cope with the rebound effects of the sanctions. Either way, Russian energy exports go back to normal and the price of Canadian energy stocks drops significantly.
The same is true when it comes to China and its COVID lockdowns. They may be driving up the price of the US dollar right now, but things will soon get back to normal. China’s approach of implementing harsh lockdowns ensures that they last the minimum amount of time. This is already happening, with China’s economy just experiencing its best month since February.
This is not to say that Canadian energy stocks are a bad investment. But, if you are to invest in these stocks, you need to be prepared to watch the market carefully. Things can change in an instant, and you can see your investment lose its value.
How do scientists know the right dose of a drug? How long does it stay in the body? And how does it actually work once it gets there?
The answers lie in PK/PD—short for pharmacokinetics and pharmacodynamics—two key concepts that shape how medicines are developed, tested, and refined.
To understand how these two fields guide drug research, it helps to break down what each one actually means.
1. PK/PD Defined in Plain Terms
Pharmacokinetics (PK) tracks what the body does to a drug—how it’s absorbed, distributed, metabolized, and excreted. In contrast, pharmacodynamics (PD) looks at what the drug does to the body—its biological effects and how those effects change with dose or time.
Together, they help researchers fine-tune every stage of drug development—from preclinical studies to dosing decisions.
2. Why Timing Is Everything in PK
Timing isn’t just important; it’s everything. PK shows you how fast a drug gets into the bloodstream, how long it stays active, and when it leaves the body.
That knowledge drives key decisions about medication schedules. Should it be taken once a day or several times? Swallowed or injected? The PK profile helps answer those questions.
PK also makes it possible to track how drug concentrations rise and fall over time, depending on the dose and how the body processes it. Finding the right balance—enough to be effective but not enough to cause harm—is key to designing safe and effective clinical studies.
3. PD Tells You If a Drug Works
Once the drug reaches its target, PD shows what kind of response it triggers in the body. Does it bind to the right receptor? Block a harmful process? PD helps you measure those effects and determine if the drug is doing what it’s supposed to do.
PD data also helps identify when that response starts to fade or becomes too strong. It’s useful for assessing if the drug’s action is strong enough, lasts long enough, and stays within a safe range.
4. PK/PD Models Guide Early Decisions
Before human trials begin, PK/PD modeling is used to predict how a drug might behave in the body. It often relies on preclinical data from animal studies and can simulate a variety of conditions, including how a drug may act in individuals with critical illness.
To use these tools effectively, researchers often consult expert-developed resources that cover essential PK/PD modeling techniques, from foundational principles to advanced applications.
With strong modeling skills, it becomes easier to identify potential issues early, optimize clinical study design, and reduce trial-and-error. This leads to more focused, efficient early-phase research.
5. Animal Data Isn’t Enough
Animal studies provide an important starting point in drug research. They can reveal how a compound behaves and highlight possible risks, like toxicity or poor absorption. But since animals and humans process drugs differently, their results don’t always translate directly.
This is where PK/PD analysis becomes critical. It helps adjust and interpret preclinical findings in a way that’s relevant to human biology. Accurate bioanalytical methods are also needed to track how drugs move through different systems. Without that, early signals could be
misleading.
6. PK/PD Supports Personalized Treatment
People vary in how they respond to medications. A dose that’s right for one person might be too strong—or too weak—for someone else. PK/PD allows for adjustments based on individual factors like age, weight, liver or kidney function, genetics, and other medications.
This kind of personalization improves safety and effectiveness, and it’s becoming an increasingly common goal in clinical pharmacology.
7. Regulatory Agencies Want PK/PD
PK/PD data has become a core part of regulatory review. Agencies like the Food and Drug Administration (FDA) and other regulatory authorities around the world look for this information in drug submissions. It helps explain how a drug works, how its dosage was chosen, and how
safe it appears to be.
This data also supports study design, safety assessments, and the information included on the final drug label. Submissions without it are more likely to face questions, delays, or rejections.
8. PK/PD Helps Uncover Safety Issues
While PK/PD is often associated with measuring effectiveness, it also plays a significant role in identifying safety concerns. It can reveal issues like drug accumulation, interactions with other medications, or delayed side effects.
By connecting drug exposure to those risks, adjustments can be made early, well before the drug reaches a broader population. That leads to safer trials and better long-term outcomes.
9. PK/PD Keeps Evolving
The field of PK/PD is advancing quickly. Better tools and smarter technology are changing how drug behavior is modeled and understood. Machine learning, big data, and improved bioanalytical methods are making it easier to anticipate how drugs will perform under real-world
conditions.
These advances support more reliable predictions and allow teams to adapt faster, either during early testing or when refining late-stage development plans.
Final Thoughts
PK/PD may seem technical at first, but its value is hard to miss. It plays a critical role in making sure new drugs are safe, effective, and precisely delivered. Understanding how these principles guide drug research offers a clearer view of the science behind the medicines we depend on.
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