Connect with us
[the_ad id="89560"]

Uncategorized

3 win chemistry Nobel; findings led to bestselling drug

Published

5 minute read

STOCKHOLM — Three researchers who “harnessed the power of evolution” to produce enzymes and antibodies that have led to a new bestselling drug and biofuels won the Nobel Prize in chemistry on Wednesday.

Frances Arnold of the California Institute of Technology was awarded half of the 9-million-kronor ($1.01 million) prize, while the other half will be shared by George Smith of the University of Missouri and Gregory Winter of the MRC molecular biology lab in Cambridge, England.

The Royal Swedish Academy of Sciences, which chose the winners, said Arnold, 62, conducted the first directed evolution of enzymes, whose uses include “more environmentally friendly manufacturing of chemical substances such as pharmaceuticals and the production of renewable fuels.”

Smith, 77, developed a method to evolve new proteins and Winter used the method to evolve antibodies, which are disease-fighting proteins in the blood.

The first pharmaceutical based on Winter’s work was approved for use in 2002 and is employed to treat rheumatoid arthritis, psoriasis and inflammatory bowel diseases, the academy said. The chemical name of the drug is adalimumab, which has several trade named including Humira, one of the top-selling drugs in the world.

Smith, speaking to The Associated Press after learning about this Nobel win, credited others for the work that led to his breakthrough.

“Very few research breakthroughs are novel. Virtually all of them build on what went on before. It’s happenstance. That was certainly the case with my work,” he said Wednesday. “Mine was an idea in a line of research that built very naturally on the lines of research that went before.”

Smith said he learned of the prize in a pre-dawn phone call from Stockholm.

“It’s a standard joke that someone with a Swedish accent calls and says ‘You won!’ But there was so much static on the line, I knew it wasn’t any of my friends,” he said.

American Chemical Society president Peter Dorhout praised the Nobel winners, saying “the laureates have used chemistry to accelerate the evolution of natural biological molecules that act as the critical machinery for living organisms.

“The breakthroughs from these researchers enable that to occur thousands of times faster than nature to improve medicines, fuels and other products,” he said.

Experts said the developments for which the winners won the 2018 prize can be more ecological than many other chemical processes.

Enzymes “are what all we organisms use to make our chemicals. So if you can harness enzymes for your own purposes, this is often more environmentally friendly than using heavy metals or toxic substances to make your chemicals,” said Johan Aqvist, a member of the Nobel Committee for Chemistry.

In other Nobel prizes this year, the medicine prize went Monday to James Allison of the University of Texas M.D. Anderson Cancer Center and Tasuku Honjo of Kyoto University, who learned how to release the brakes that cancer can put on the immune system, discoveries that helped cancer doctors fight many advanced-stage tumors and save an “untold” numbers of lives.

Scientists from the United States, Canada and France shared the physics prize Tuesday for revolutionizing the use of lasers in research.

Arthur Ashkin became the oldest Nobel Prize laureate at 96, while Donna Strickland of the University of Waterloo in Canada became only the third woman to win a physics Nobel. Strickland had worked with the third winner, Frenchman Gerard Mourou of the Ecole Polytechnique and the University of Michigan.

The winner of the Nobel Peace Prize is to be announced Friday. The Nobel Memorial Prize in Economic Sciences, honouring Alfred Nobel, the man who endowed the five Nobel Prizes, will be revealed on Monday.

No Nobel literature prize will be awarded this year due to a sex abuse scandal at the Swedish Academy, which choses the winner. The academy plans to announce both the 2018 and the 2019 winner next year — although the head of the Nobel Foundation has said the body must fix its tarnished reputation first.

The man at the centre of the Swedish Academy scandal, Jean-Claude Arnault, a major cultural figure in Sweden, was sentenced Monday to two years in prison for rape.

___

Heintz reported from Moscow. Malcolm Ritter and Chris Chester in New York contributed to this story.

Jim Heintz And David Keyton, The Associated Press






Before Post

Storytelling is in our DNA. We provide credible, compelling multimedia storytelling and services in English and French to help captivate your digital, broadcast and print audiences. As Canada’s national news agency for 100 years, we give Canadians an unbiased news source, driven by truth, accuracy and timeliness.

Follow Author

Uncategorized

Conservative MP Leslyn Lewis calls out Liberals for not supporting anti-church burning bill

Published on

From LifeSiteNews

By Anthony Murdoch

Speaking about the ‘hundreds of churches’ that have been ‘set on fire across Canada’ in the last number of years, Conservative MP Leslyn Lewis questioned why the Liberals seem completely unconcerned.

One of Canada’s most prominent pro-life MPs has called out the Trudeau government for its apparent lack of support for an anti-arson bill which aims to curb the rash of church burnings plaguing Christians in the country.

In an X post Monday, Conservative MP Leslyn Lewis pointed out that under the Liberal government of Prime Minister Justin Trudeau, church burnings have shot up “100 percent,” and that the government does not seem to have expressed any “concern” at all.

“In the last several years, hundreds of churches and other places of worship have been set on fire across Canada. Under this Liberal government, these crimes have increased by over 100%,” wrote Lewis on X.  

“Where is the concern or action from the Liberals regarding these attacks on Christian churches?” 

Lewis’s post included a link to another X post from Conservative MP Marc Dalton, who posted a video on October 31 highlighting the recent rash of church burnings and how his bill, C-411, aims to stop this.  

“Thank you @MarcDalton for bringing forward Bill C-411, the Anti-Arson Act, an important bill to protect places of worship and increase penalties on those who would target them,” wrote Lewis. 

Bill C-411, or, An Act to amend the Criminal Code (arson — wildfires and places of worship),  was introduced by Dalton in June. 

The law, if passed, would create specific criminal offenses for setting fires to churches and for starting wildfires.

Dalton said in his video that there is a “serious problem in Canada that must be addressed” concerning Catholic and Christian churches being the target of arson. 

He highlighted how since 2010, 592 churches have been the target of arson in Canada, with a large portion of these being concentrated to the last few years.  

Dalton noted how Canada’s Criminal Code, as it stands, does not include specific protections against arson directed at religious institutions. C-411 aims to “change that,” said Dalton, noting that the bill would implement a minimum sentence of five years in jail for a first offense of this kind, and seven years for a repeat offense.

“This bill strengthens our criminal code and punishes these hateful arson attacks,” he said. 

“Commonsense Conservatives stand for strict punishments against criminals who target places of worship.” 

Since the spring of 2021, 112 churches, most of them Catholic, have beenburned to the ground, vandalized or defiled in Canada. 

The church burnings started in earnest after the mainstream media and the federal government ran with inflammatory and dubious claims that hundreds of children were buried and disregarded by Catholic priests and nuns who ran some of the now-closed residential schools in Canada, particularly a school in Kamloops, British Columbia.

The anti-Catholic narrative that developed following these claims continues to this day, despite the fact that no bodies have actually been discovered.

Continue Reading

Uncategorized

Firm tied to voter registration ‘scheme’ goes dark

Published on

From left, Lancaster County Commissioner Alice Yoder, Lancaster County District Attorney Heather Adams, Commissioners Ray D’Agostino and Josh Parsons. The officials held a press conference on Friday, Oct. 25, 2024, to discuss voter registration fraud detected in the county.

From The Center Square

By 

Everybody Votes runs an office in Lancaster County, where election workers recently found suspicious registration forms among a batch of 2,500 applications delivered last week. Investigators there said at least 60% of those reviewed were fraudulent.

The media and consulting firm linked to fraudulent voter registration forms in Pennsylvania earlier this week has gone dark as of Saturday.

Field and Media Corps – the website and social media accounts of which are now defunct – is an Arizona-based company that contracts with Everybody Votes to run a canvassing operation in Pennsylvania and other states that target low-income minority residents unregistered to vote.

The Monroe County District Attorney’s Office confirmed Wednesday that 30 registration forms contained fraudulent information, including an application submitted on behalf of a dead resident.

Everybody Votes runs an office in Lancaster County, where election workers recently found suspicious registration forms among a batch of 2,500 applications delivered last week. Investigators there said at least 60% of those reviewed were fraudulent. So far, the campaign has not been tied directly to the investigation.

Not so in nearby York County, where law enforcement continues reviewing another delivery from the operation leading up to the Oct. 22 deadline to register.

On Wednesday, the America First Policy Institute, a conservative-leaning research nonprofit,  demanded a federal investigation into the company.

“Where there’s fire, there’s fire,” said Hogan Gidley, vice chairman of the institute’s Center for Election Integrity. “Thousands of instances of reported voter registration fraud have now been confirmed throughout Pennsylvania.”

He described Field and Media Corps, established in 2017, as a “high-powered left-wing organization” that may have launched similar “schemes” across the country that require state-level investigations.

“Submitting fraudulent registrations right at the voter deadline to overwhelm election officials is exactly the kind of scheme that the Department of Justice should be using their force and resources to stop,” he said.

Evidence also exists that Everybody Votes is linked to a left-wing super political action committee intent on expanding registration numbers for Democrats in battleground states.

According to public tax records shared with The Center Square, The Voter Registration Project, also known as Everybody Votes, describes itself as a public charity that helps low-income minority citizens register to vote and provides technical assistance to voter registration drives.

The organization reported $45.8 million in total revenues in 2022, a “substantial portion of which comes from a governmental unit or the general public.”

A 2023 report from Capital Research Center, a conservative nonprofit, says left-wing donors together raised $190 million for the campaign to register 5.1 million voters across the country – all in violation of federal law that bars 501(c)(3) from engaging in such activity.

The strategy, detailed in a 2019 leaked memo from Mind the Gap, the liberal super PAC in question, entices investors by promising a more cost-effective strategy to boost vote counts for Democrats – namely through voter registration drives.

The group pointed to its direct role in flipping the U.S. House blue in 2018 as “proof of concept.”

Detailed further in the report are signed tax forms from donors that link their grants to the Voter Registration Project in direct support of Mind the Gap. The Capital Research Center estimates President Joe Biden collected between 1 million and 2.7 million swing state votes in the 2020 election as a result.

Biden defeated then-incumbent President Donald Trump 306-232 in electoral college votes; the popular vote was Biden 81.2 million to 74.2 million.

Francisco Heredia, who runs Field and Media Corps, told Votebeat earlier this week he’d not heard from county officials in Pennsylvania, but would cooperate with the investigation. He said the company trains workers how to legally complete registration forms and has no tolerance for fraud.

Continue Reading

Trending

X