Brownstone Institute
Pfizer Lied to Us Again
From Brownstone Institute
There used to be a time where claims from pharmaceutical companies may have been treated with some degree of skepticism from major institutions and media outlets.
Yet in late 2020 and into 2021, suddenly skepticism turned to complete blind faith. But what changed? Why, political incentives, of course!
Initially, Covid vaccines produced by Pfizer were seen as dangerous and untested; they were considered a Trump vaccine that only idiots who were willing to risk their own health would take. However when the 2020 election had been officially decided, and Biden and his political allies represented the Covid vaccines as the pathway out of the pandemic, a moral choice that would help yourself and others, narratives and incentives changed dramatically.
Pfizer became a heroic symbol of virtue, and all questioning of Covid vaccines was grounds for immediate expulsion from polite society, regardless of the actual efficacy of Pfizer’s products.
Much of the blame for the vaccines’ underperformance could be placed on Pfizer itself; the company relentlessly promoted hopelessly inaccurate efficacy estimates and supported efforts to unnecessarily mandate mRNA shots.
Sure enough, on the back of progressive orthodoxy, corporate and institutional incompetence and media activism, they proudly reported record revenues.
We all know how that turned out in 2022 and 2023.
Skepticism towards Pfizer’s vaccine was obviously quite well warranted. And it turns out that now we, and of course, Pfizer’s chief promoters in the media and public health class should have been even more skeptical.
They weren’t.
Pfizer’s Claims On Covid Treatments Were Wildly Inaccurate
As the Covid vaccines failed spectacularly to stop the spread of infections and did nothing to lessen all-cause mortality or even decrease population level Covid-associated deaths in highly vaccinated countries, Pfizer saw another opportunity.
Sure, their signature product failed to perform as expected. So why not create another one as an antidote?
Enter Paxlovid.
Paxlovid, an antiviral drug, was supposed to help individuals with symptomatic Covid, who’d already been infected, recover more quickly and lessen the risk of severe illness. Sounds great right?
It would appear that it sure did to Anthony Fauci and the cadre of media-promoted “experts.”
Fauci praised Paxlovid in 2022, after the mRNA vaccines and booster doses failed to prevent him from contracting Covid. Bizarrely, Fauci implied that the same Pfizer products that he demanded everyone take would not have been enough to keep him healthy, saying that he believed Paxlovid had kept him out of the hospital.
Never mind, of course, that Fauci had a “rebound” case of Covid-19 after taking Paxlovid and getting vaccinated and boosted. Acknowledging imperfections would undercut his desire to get everyone to take more of his preferred products.
Paxlovid made headlines again later in 2022 as Rochelle Walensky also praised Pfizer’s efforts, despite once again testing positive for “rebound” Covid after Paxlovid treatments.
Even today, the CDC’s own website says Paxlovid is an “effective” treatment for those who’ve contracted the virus and want to avoid severe illness.
There’s just one problem; it’s not true.
A newly released study on Paxlovid on randomized adults with symptomatic Covid; one subset was given Paxlovid (nirmatrelvir-ritonavir) or a placebo every 12 hours for five days, with the intent of determining how effective it was at “sustained alleviation” of Covid-19 symptoms.
In this phase 2–3 trial, we randomly assigned adults who had confirmed Covid-19 with symptom onset within the past 5 days in a 1:1 ratio to receive nirmatrelvir–ritonavir or placebo every 12 hours for 5 days. Patients who were fully vaccinated against Covid-19 and who had at least one risk factor for severe disease, as well as patients without such risk factors who had never been vaccinated against Covid-19 or had not been vaccinated within the previous year, were eligible for participation. Participants logged the presence and severity of prespecified Covid-19 signs and symptoms daily from day 1 through day 28. The primary end point was the time to sustained alleviation of all targeted Covid-19 signs and symptoms. Covid-19–related hospitalization and death from any cause were also assessed through day 28.
Spoiler alert: it wasn’t effective at all.
Their measured results revealed that there was effectively no difference whatsoever in the “sustained alleviation” of symptoms between Paxlovid and a placebo. Those taking Pfizer’s miracle antiviral treatment saw their “signs and symptoms” resolve after 12 days, while the placebo recipients took 13 days.
The median time to sustained alleviation of all targeted signs and symptoms of Covid-19 was 12 days in the nirmatrelvir–ritonavir group and 13 days in the placebo group (P=0.60). Five participants (0.8%) in the nirmatrelvir–ritonavir group and 10 (1.6%) in the placebo group were hospitalized for Covid-19 or died from any cause (difference, −0.8 percentage points; 95% confidence interval, −2.0 to 0.4).
This is the product that to this day is relentlessly promoted by the CDC, the media, and politicians as an effective tool to reduce the severity of symptoms and the length of illness. And it was virtually meaningless.
Even with regards to the most severe outcomes, hospitalization, and death, the difference was negligible. Confidence intervals for the difference in outcome even stretched to a positive relationship, meaning that it’s within the bounds of possibility that more people died or were hospitalized after taking Paxlovid than a placebo.
Succinctly, the researchers confirmed in their summary that there was no difference between the two treatments.
The time to sustained alleviation of all signs and symptoms of Covid-19 did not differ significantly between participants who received nirmatrelvir–ritonavir and those who received placebo.
But who are these researchers, you might ask…surely they’re fringe scientists, desperate to undercut a big, bad pharmaceutical company, right? How else could their conclusions so thoroughly undermine Pfizer?
Let’s take a look at the disclosure to see who funded this study, designed the trial, conducted it, collected the data, and analyzed the results. Surely, that will reveal the nefarious intentions behind this dastardly attempt to cut at the heart of Pfizer’s miracle drug.
Pfizer was responsible for the trial design and conduct and for data collection, analysis, and interpretation. The first draft of the manuscript was written by medical writers (funded by Pfizer) under direction from the authors.
Oh. Oh no.
Pfizer created the trial, conducted it, collected the data, and analyzed it. And it found that Paxlovid made no difference to the resolution of symptoms or with keeping people alive or out of the hospital. That has to sting.
Even worse, Covid vaccination was once again proven to be almost entirely irrelevant where results were concerned. Results were the same between “high-risk subgroups,” meaning those who had been vaccinated but had an elevated risk for more serious symptoms, and those who had never been vaccinated or had received the last dose more than a year ago.
Similar results were observed in the high-risk subgroup (i.e., participants who had been vaccinated and had at least one risk factor for severe illness) and in the standard-risk subgroup (i.e., those who had no risk factors for severe illness and had never been vaccinated or had not been vaccinated within the previous 12 months).
So not only did Paxlovid not make a difference, but vaccination status AND Paxlovid wasn’t enough to create a sizable gap in outcomes between healthy, unvaccinated individuals.
But wait, there’s more.
Viral load rebounds were also more common in the Paxlovid group, and symptom and viral load rebounds combined were more common among those taking Pfizer’s treatment. While percentages were generally low, other studies have pegged Paxlovid-associated rebound as occurring nearly one quarter of the time.
So it’s not particularly effective at reducing symptoms or resolving them more quickly, doesn’t lead to statistically significant improvements in the most severe outcomes, and is more likely to result in a rebound case of the illness it’s supposed to be protecting you from.
Sounds exactly like the type of product that Fauci, Walensky, and the CDC would praise, doesn’t it?
Paxlovid is the entire Covid-pharmaceutical complex summarized perfectly. Created to solve a problem that was supposed to be fixed by another product…understudied, overhyped by the “experts,” and prematurely authorized by a desperate FDA…and ultimately shown to be mostly ineffective.
Once again, the actual science disproves The Science™. And once again, we’ll get no acknowledgment of it or apologies for the billions of taxpayer dollars wasted. Can’t wait to see what Pfizer does for an encore.
Republished from the author’s Substack
Author
From the Brownstone Institute
Way back in the B.C. era (Before Covid), I taught Medical Humanities and Bioethics at an American medical school. One of my older colleagues – I’ll call him Dr. Quinlan – was a prominent member of the faculty and a nationally recognized proponent of physician-assisted suicide.
Dr. Quinlan was a very nice man. He was soft-spoken, friendly, and intelligent. He had originally become involved in the subject of physician-assisted suicide by accident, while trying to help a patient near the end of her life who was suffering terribly.
That particular clinical case, which Dr. Quinlan wrote up and published in a major medical journal, launched a second career of sorts for him, as he became a leading figure in the physician-assisted suicide movement. In fact, he was lead plaintiff in a challenge of New York’s then-prohibition against physician-assisted suicide.
The case eventually went all the way to the US Supreme Court, which added to his fame. As it happened, SCOTUS ruled 9-0 against him, definitively establishing that there is no “right to die” enshrined in the Constitution, and affirming that the state has a compelling interest to protect the vulnerable.
SCOTUS’s unanimous decision against Dr. Quinlan meant that his side had somehow pulled off the impressive feat of uniting Antonin Scalia, Ruth Bader Ginsberg, and all points in between against their cause. (I never quite saw how that added to his luster, but such is the Academy.)
At any rate, I once had a conversation with Dr. Quinlan about physician-assisted suicide. I told him that I opposed it ever becoming legal. I recall he calmly, pleasantly asked me why I felt that way.
First, I acknowledged that his formative case must have been very tough, and allowed that maybe, just maybe, he had done right in that exceptionally difficult situation. But as the legal saying goes, hard cases make bad law.
Second, as a clinical physician, I felt strongly that no patient should ever see their doctor and have to wonder if he was coming to help keep them alive or to kill them.
Finally, perhaps most importantly, there’s this thing called the slippery slope.
As I recall, he replied that he couldn’t imagine the slippery slope becoming a problem in a matter so profound as causing a patient’s death.
Well, maybe not with you personally, Dr. Quinlan, I thought. I said no more.
But having done my residency at a major liver transplant center in Boston, I had had more than enough experience with the rather slapdash ethics of the organ transplantation world. The opaque shuffling of patients up and down the transplant list, the endless and rather macabre scrounging for donors, and the nebulous, vaguely sinister concept of brain death had all unsettled me.
Prior to residency, I had attended medical school in Canada. In those days, the McGill University Faculty of Medicine was still almost Victorian in its ways: an old-school, stiff-upper-lip, Workaholics-Anonymous-chapter-house sort of place. The ethic was hard work, personal accountability for mistakes, and above all primum non nocere – first, do no harm.
Fast forward to today’s soft-core totalitarian state of Canada, the land of debanking and convicting peaceful protesters, persecuting honest physicians for speaking obvious truth, fining people $25,000 for hiking on their own property, and spitefully seeking to slaughter harmless animals precisely because they may hold unique medical and scientific value.
To all those offenses against liberty, morality, and basic decency, we must add Canada’s aggressive policy of legalizing, and, in fact, encouraging industrial-scale physician-assisted suicide. Under Canada’s Medical Assistance In Dying (MAiD) program, which has been in place only since 2016, physician-assisted suicide now accounts for a terrifying 4.7 percent of all deaths in Canada.
MAiD will be permitted for patients suffering from mental illness in Canada in 2027, putting it on par with the Netherlands, Belgium, and Switzerland.
To its credit, and unlike the Netherlands and Belgium, Canada does not allow minors to access MAiD. Not yet.
However, patients scheduled to be terminated via MAiD in Canada are actively recruited to have their organs harvested. In fact, MAiD accounts for 6 percent of all deceased organ donors in Canada.
In summary, in Canada, in less than 10 years, physician-assisted suicide has gone from illegal to both an epidemic cause of death and a highly successful organ-harvesting source for the organ transplantation industry.
Physician-assisted suicide has not slid down the slippery slope in Canada. It has thrown itself off the face of El Capitan.
And now, at long last, physician-assisted suicide may be coming to New York. It has passed the House and Senate, and just awaits the Governor’s signature. It seems that the 9-0 Supreme Court shellacking back in the day was just a bump in the road. The long march through the institutions, indeed.
For a brief period in Western history, roughly from the introduction of antibiotics until Covid, hospitals ceased to be a place one entered fully expecting to die. It appears that era is coming to an end.
Covid demonstrated that Western allopathic medicine has a dark, sadistic, anti-human side – fueled by 20th-century scientism and 21st-century technocratic globalism – to which it is increasingly turning. Physician-assisted suicide is a growing part of this death cult transformation. It should be fought at every step.
I have not seen Dr. Quinlan in years. I do not know how he might feel about my slippery slope argument today.
I still believe I was correct.
From the Brownstone Institute
Many news outlets reported the announcement of the Nobel Peace Prize on Friday by saying President Donald Trump had missed out (Washington Post, Yahoo, Hindustan Times, Huffington Post), not won (USA Today), fallen short (AP News), lost (Time), etc. There is even a meme doing the rounds about ‘Trump Wine.’ ‘Made from sour grapes,’ the label explains, ‘This is a full bodied and bitter vintage guaranteed to leave a nasty taste in your mouth for years.’
For the record, the prize was awarded to María Corina Machado for her courageous and sustained opposition to Venezuela’s ruling regime. Trump called to congratulate her. Given his own attacks on the Venezuelan president, his anger will be partly mollified, and he could even back her with practical support. He nonetheless attacked the prize committee, and the White House assailed it for putting politics before peace.
He could be in serious contention next year. If his Gaza peace plan is implemented and holds until next October, he should get it. That he is unlikely to do so is more a reflection on the award and less on Trump.
So He Won the Nobel Peace Prize. Meh!
Alfred Nobel’s will stipulates the prize should be awarded to the person who has contributed the most to promote ‘fraternity between nations…abolition or reduction of standing armies and…holding and promotion of peace congresses.’ Over the decades, this has expanded progressively to embrace human rights, political dissent, environmentalism, race, gender, and other social justice causes.
On these grounds, I would have thought the Covid resistance should have been a winner. The emphasis has shifted from outcomes and actual work to advocacy. In honouring President Barack Obama in 2009, the Nobel committee embarrassed itself, patronised him, and demeaned the prize. His biggest accomplishment was the choice of his predecessor as president: the prize was a one-finger send-off to President George W. Bush.
There have been other strange laureates, including those prone to wage war (Henry Kissinger, 1973), tainted through association with terrorism (Yasser Arafat, 1994), and contributions to fields beyond peace, such as planting millions of trees. Some laureates were subsequently discovered to have embellished their record, and others proved to be flawed champions of human rights who had won them the treasured accolade.
Conversely, Mahatma Gandhi did not get the prize, not for his contributions to the theory and practice of non-violence, nor for his role in toppling the British Raj as the curtain raiser to worldwide decolonisation. The sad reality is how little practical difference the prize has made to the causes it espoused. They bring baubles and honour to the laureates, but the prize has lost much of its lustre as far as results go.
Trump Was Not a Serious Contender
The nomination processes start in September and nominations close on 31 January. The five-member Norwegian Nobel committee scrutinises the list of candidates and whittles it down between February and October. The prize is announced on or close to 10 October, the date Alfred Nobel died, and the award ceremony is held in Oslo in early December.
The calendar rules out a newly elected president in his first year, with the risible exception of Obama. The period under review was 2024. Trump’s claims to have ended seven wars and boasts of ‘nobody’s ever done that’ are not taken seriously beyond the narrow circle of fervent devotees, sycophantic courtiers, and supplicant foreign leaders eager to ingratiate themselves with over-the-top flattery.
Trump Could Be in Serious Contention Next Year
Trump’s 20-point Gaza peace plan falls into three conceptual-cum-chronological parts: today, tomorrow, and the day after. At the time of writing, in a hinge moment in the two-year war, Israel has implemented a ceasefire in Gaza, Hamas has agreed to release Israeli hostages on 13-14 October, and Israel will release around 2,000 Palestinian prisoners (today’s agenda). So why are the ‘Ceasefire Now!’ mobs not out on the streets celebrating joyously instead of looking morose and discombobulated? Perhaps they’ve been robbed of the meaning of life?
The second part (tomorrow) requires Hamas demilitarisation, surrender, amnesty, no role in Gaza’s future governance, resumption of aid deliveries, Israeli military pullbacks, a temporary international stabilisation force, and a technocratic transitional administration. The third part, the agenda for the day after, calls for the deradicalisation of Gaza, its reconstruction and development, an international Peace Board to oversee implementation of the plan, governance reforms of the Palestinian Authority, and, over the horizon, Palestinian statehood.
There are too many potential pitfalls to rest easy on the prospects for success. Will Hamas commit military and political suicide? How can the call for democracy in Gaza and the West Bank be reconciled with Hamas as the most popular group among Palestinians? Can Israel’s fractious governing coalition survive?
Both Hamas and Israel have a long record of agreeing to demands under pressure but sabotaging their implementation at points of vulnerability. The broad Arab support could weaken as difficulties arise. The presence of the internationally toxic Tony Blair on the Peace Board could derail the project. Hamas has reportedly called on all factions to reject Blair’s involvement. Hamas official Basem Naim, while thanking Trump for his positive role in the peace deal, explained that ‘Palestinians, Arabs and Muslims and maybe a lot [of] people around the world still remember his [Blair’s] role in causing the killing of thousands or millions of innocent civilians in Afghanistan and Iraq.’
It would be a stupendous achievement for all the complicated moving parts to come together in stable equilibrium. What cannot and should not be denied is the breathtaking diplomatic coup already achieved. Only Trump could have pulled this off.
The very traits that are so offputting in one context helped him to get here: narcissism; bullying and impatience; bull in a china shop style of diplomacy; indifference to what others think; dislike of wars and love of real estate development; bottomless faith in his own vision, negotiating skills, and ability to read others; personal relationships with key players in the region; and credibility as both the ultimate guarantor of Israel’s security and preparedness to use force if obstructed. Israelis trust him; Hamas and Iran fear him.
The combined Israeli-US attacks to degrade Iran’s nuclear capability underlined the credibility of threats of force against recalcitrant opponents. Unilateral Israeli strikes on Hamas leaders in Qatar highlighted to uninvolved Arabs the very real dangers of continued escalation amidst the grim Israeli determination to rid themselves of Hamas once and for all.
Trump Is Likely to Be Overlooked
Russia has sometimes been the object of the Nobel Peace Prize. The mischievous President Vladimir Putin has suggested Trump may be too good for the prize. Trump’s disdain for and hostility to international institutions and assaults on the pillars of the liberal international order would have rubbed Norwegians, among the world’s strongest supporters of rules-based international governance, net zero, and foreign aid, the wrong way.
Brash and public lobbying for the prize, like calling the Norwegian prime minister, is counterproductive. The committee is fiercely independent. Nominees are advised against making the nomination public, let alone orchestrating an advocacy campaign. Yet, one laureate is believed to have mobilised his entire government for quiet lobbying behind the scenes, and another to have bad-mouthed a leading rival to friendly journalists.
Most crucially, given that Scandinavian character traits tip towards the opposite end of the scale, it’s hard to see the committee overlooking Trump’s loud flaws, vanity, braggadocio, and lack of grace and humility. Trump supporters discount his character traits and take his policies and results seriously. Haters cannot get over the flaws to seriously evaluate policies and outcomes. No prizes for guessing which group the Nobel committee is likely to belong to. As is currently fashionable to say when cancelling someone, Trump’s values do not align with those of the committee and the ideals of the prize.
Author
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