Addictions
Critics question conclusions of new Ontario “safer supply” study
A new study links safer supply to health improvements, but critics say results are muddied by methadone use and extra supports
A new study that compares safer supply with a traditional approach to addiction treatment has ignited debate among addiction experts.
The study, published in The Lancet Public Health in April, examined health outcomes for people receiving safer supply and compared them to a similar group of people receiving methadone, a drug used to reduce drug cravings and withdrawal symptoms.
It concluded that safer supply programs significantly improved participants’ health outcomes. Safer supply provides people at high risk of overdose with prescription opioids as a safer alternative to toxic street drugs.
But critics question the study’s conclusions. They note that many safer supply participants had access to more support services and that the majority also received methadone. These factors make it difficult to identify which treatment drove the positive results.
“The study did not compare [safer supply] to methadone, but rather the initiation of both with several other unaccounted variables,” wrote psychiatrists Dr. Robert Tanguaya and Dr. Nickie Mathew in a formal critique also published in The Lancet.
Findings
The peer-reviewed study is the first in Canada to compare the health outcomes for people receiving safer supply with those receiving methadone through a program known as opioid agonist therapy. Opioid agonist therapy, or OAT, is widely used to treat opioid use disorder.
The study, which was led by teams at Unity Health Toronto, ICES, the University of Toronto and the Ontario Network of People Who Use Drugs, followed about 1,700 Ontarians who started treatment between 2016 and 2021. Half were receiving prescribed hydromorphone through Ontario’s safer supply programs; the other half were receiving methadone through an OAT program.
Participants were tracked for up to one year. Both groups saw improvements, including fewer overdoses, emergency room visits, hospital stays and new infections.
“The findings suggest [safer supply] programs play an important, complementary role to traditional opioid agonist treatment in expanding the options available to support people who use drugs,” the study says.
However, when compared against each other, the safer supply group had higher rates of overdose, ER visits and hospital admissions than those on methadone.
Still, the authors conclude that safer supply can complement methadone, especially for people who do not respond well to traditional options like OAT.
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Confounders
In their May 27 critique in The Lancet Public Health, psychiatrists Tanguay and Mathew say the study fails to isolate the effects of safer supply.
“It is unclear from this study whether the benefits attributed to [safer supply] initiation came from the prescribed … hydromorphone or not,” they wrote.
One concern is that most safer supply participants were also on methadone — a highly dose-dependent medication — and the study did not account for how much of each drug they received.
Dr. Leonara Regenstreif, a primary care physician who specializes in substance use disorders, raised a similar point in an email to Canadian Affairs.
She noted that 84 per cent of safer supply participants in the study were already on methadone when they began receiving hydromorphone.
“It would take a lot of fudging to be able to say [safer supply] was responsible for an outcome, when that group was actually receiving two drugs,” she said.
The main study’s authors did not respond to requests for comment. Instead, they directed Canadian Affairs to their May 27 response to Tanguay and Mathew’s critique, also published in The Lancet.
Wraparound care
Critics also say that improved outcomes among safer supply participants may be due to the extensive additional health care they received while on safer supply.
This additional care was evidenced in study participants’ medication costs.
In the year after treatment began, median medication costs for safer supply patients rose by more than $13,000 per person. By comparison, costs for those on methadone rose by about $1,600.
Glen McGee, a statistics professor at the University of Waterloo, says this suggests safer supply participants may have received broader care, including treatment for other conditions like HIV or hepatitis C.
“This could suggest treatment [of the safer supply group] involved more thorough care in addition to [safer supply], which could also account for some of the improved outcomes,” he said.
In their response to Tanguay and Mathew’s critique, the main study’s authors said the additional care is not a flaw — it reflects how Ontario’s safer supply model is designed.
“Embedding hydromorphone prescriptions within other health and social services that address the complex needs of people at high risk of drug-related harms is a deliberate and defining feature,” they wrote.
McGee suggests the challenge of isolating the impact of broader care makes it difficult to draw broad conclusions about safer supply’s role in patients’ health outcomes.
“The analyses in the main paper seem reasonable, but the conclusions are perhaps too strong,” said McGee. “We don’t necessarily know if [safer supply] alone would be as effective.”
Overdose risk
Critics also focused on safer supply participants having a higher risk of overdose than those in opioid agonist therapy.
Although safer supply patients were more likely to stay in treatment than methadone patients, overdose rates remained higher for safer supply patients — even after adjusting for people who dropped out from the methadone group.
The study authors say this is likely because safer supply patients started at higher risk and many continued using street drugs early in treatment.
“The smaller decline among [safer supply] recipients might reflect higher baseline risk and greater ongoing exposure to the unregulated drug supply early in treatment,” they wrote.
They also noted that very few people died in either group, showing that treatment — whether safer supply or methadone — offers protection.
However, Regenstreif urges caution.
“If you peel away the stats language, underneath it all you have a cohort with higher risks of opioid toxicity and other hazards of ongoing drug use,” said Regenstreif.
This article was produced through the Breaking Needles Fellowship Program, which provided a grant to Canadian Affairs, a digital media outlet, to fund journalism exploring addiction and crime in Canada. Articles produced through the Fellowship are co-published by Break The Needle and Canadian Affairs.
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Addictions
Canadian gov’t not stopping drug injection sites from being set up near schools, daycares
From LifeSiteNews
Canada’s health department told MPs there is not a minimum distance requirement between safe consumption sites and schools, daycares or playgrounds.
So-called “safe” drug injection sites do not require a minimum distance from schools, daycares, or even playgrounds, Health Canada has stated, and that has puzzled some MPs.
Canadian Health Minister Marjorie Michel recently told MPs that it was not up to the federal government to make rules around where drug use sites could be located.
“Health Canada does not set a minimum distance requirement between safe consumption sites and nearby locations such as schools, daycares or playgrounds,” the health department wrote in a submission to the House of Commons health committee.
“Nor does the department collect or maintain a comprehensive list of addresses for these facilities in Canada.”
Records show that there are 31 such “safe” injection sites allowed under the Controlled Drugs And Substances Act in six Canadian provinces. There are 13 are in Ontario, five each in Alberta, Quebec, and British Columbia, and two in Saskatchewan and one in Nova Scotia.
The department noted, as per Blacklock’s Reporter, that it considers the location of each site before approving it, including “expressions of community support or opposition.”
Michel had earlier told the committee that it was not her job to decide where such sites are located, saying, “This does not fall directly under my responsibility.”
Conservative MP Dan Mazier had asked for limits on where such “safe” injection drug sites would be placed, asking Michel in a recent committee meeting, “Do you personally review the applications before they’re approved?”
Michel said that “(a)pplications are reviewed by the department.”
Mazier stated, “Are you aware your department is approving supervised consumption sites next to daycares, schools and playgrounds?”
Michel said, “Supervised consumption sites were created to prevent overdose deaths.”
Mazier continued to press Michel, asking her how many “supervised consumption sites approved by your department are next to daycares.”
“I couldn’t tell you exactly how many,” Michel replied.
Mazier was mum on whether or not her department would commit to not approving such sites near schools, playgrounds, or daycares.
An injection site in Montreal, which opened in 2024, is located close to a kindergarten playground.
Conservative Party leader Pierre Poilievre has called such sites “drug dens” and has blasted them as not being “safe” and “disasters.”
Records show that the Liberal government has spent approximately $820 million from 2017 to 2022 on its Canadian Drugs and Substances Strategy. However, even Canada’s own Department of Health admitted in a 2023 report that the Liberals’ drug program only had “minimal” results.
Recently, LifeSiteNews reported that the British Columbia government decided to stop a so-called “safe supply” free drug program in light of a report revealing many of the hard drugs distributed via pharmacies were resold on the black market.
British Columbia Premier David Eby recently admitted that allowing the decriminalization of hard drugs in British Columbia via a federal pilot program was a mistake.
Former Prime Minister Justin Trudeau’s loose drug initiatives were deemed such a disaster in British Columbia that Eby’s government asked Trudeau to re-criminalize narcotic use in public spaces, a request that was granted.
Official figures show that overdoses went up during the decriminalization trial, with 3,313 deaths over 15 months, compared with 2,843 in the same time frame before drugs were temporarily legalized.
Addictions
Canada is divided on the drug crisis—so are its doctors
When it comes to addressing the national overdose crisis, the Canadian public seems ideologically split: some groups prioritize recovery and abstinence, while others lean heavily into “harm reduction” and destigmatization. In most cases, we would defer to the experts—but they are similarly divided here.
This factionalism was evident at the Canadian Society of Addiction Medicine’s (CSAM) annual scientific conference this year, which is the country’s largest gathering of addiction medicine practitioners (e.g., physicians, nurses, psychiatrists). Throughout the event, speakers alluded to the field’s disunity and the need to bridge political gaps through collaborative, not adversarial, dialogue.
This was a major shift from previous conferences, which largely ignored the long-brewing battles among addiction experts, and reflected a wider societal rethink of the harm reduction movement, which was politically hegemonic until very recently.
Recovery-oriented care versus harm reductionism
For decades, most Canadian addiction experts focused on shepherding patients towards recovery and encouraging drug abstinence. However, in the 2000s, this began to shift with the rise of harm reductionism, which took a more tolerant view of drug use.
On the surface, harm reductionists advocated for pragmatically minimizing the negative consequences of risky use—for example, through needle exchanges and supervised consumption sites. Additionally, though, many of them also claimed that drug consumption is not inherently wrong or shameful, and that associated harms are primarily caused not by drugs themselves but by the stigmatization and criminalization of their use. In their view, if all hard drugs were legalized and destigmatized, then they would eventually become as banal as alcohol and tobacco.
The harm reductionists gained significant traction in the 2010s thanks to the popularization of street fentanyl. The drug’s incredible potency caused an explosion of deaths and left users with formidable opioid tolerances that rendered traditional addiction medications, such as methadone, less effective. Amid this crisis, policymakers embraced harm reduction out of an immediate need to make drug use slightly less lethal. This typically meant supervising consumption, providing sterile drug paraphernalia, and offering “cleaner” substances for addicts to use.
Many abstinence-oriented addiction experts supported some aspects of harm reduction. They valued interventions that could demonstrably save lives without significant tradeoffs, and saw them as both transitional and as part of a larger public health toolkit. Distributing clean needles and Naloxone, an overdose-reversal medication, proved particularly popular. “People can’t recover if they’re dead,” went a popular mantra from the time.
Saving lives or enabling addiction?
However, many of these addiction experts were also uncomfortable with the broader political ideologies animating the movement and did not believe that drug use should be normalized. Many felt that some experimental harm reduction interventions in Canada were either conceptually flawed or that their implementation had deviated from what had originally been promised.
Some argued, not unreasonably, that the country’s supervised consumption sites are being mismanaged and failing to connect vulnerable addicts to recovery-oriented care. Most of their ire, however, was directed at “safer supply”—a novel strategy wherein addicts are given free drugs, predominantly hydromorphone (a heroin-strength opioid), without any real supervision.
While safer supply was meant to dissuade recipients from using riskier street drugs, addiction physicians widely reported that patients were selling their free hydromorphone to buy stronger illicit fentanyl, thereby flooding communities with diverted opioids and exacerbating the addiction crisis. They also noted that the “evidence base” behind safer supply was exceptionally poor and would not meet normal health-care standards.
Yet, critics of safer supply, and harm reduction radicalism more broadly, were often afraid to voice their opinions. The harm reductionists were institutionally and culturally dominant in the late 2010s and early 2020s, and opponents often faced activist harassment, aggressive gaslighting, and professional marginalization. A culture of self-censorship formed, giving both the public and influential policymakers a false impression of scientific consensus where none actually existed.
The resurgence in recovery-oriented strategies
Things changed in the mid-2020s. British Columbia’s failed drug decriminalization experiment eroded public trust in harm reductionism, and the scandalous failures of safer supply—and supervised consumption sites, too—were widely publicized in the national media.1
Whereas harm reductionism was once so powerful that opponents were dismissed as anti-scientific, there is now a resurgent interest in alternative, recovery-oriented strategies.
These cultural shifts have fuelled a more fractious, but intellectually honest, national debate about how to tackle the overdose crisis. This has ruptured the institutional dominance enjoyed by harm reductionists in the addiction medicine world and allowed their previously silenced opponents to speak up.
When I first attended CSAM’s annual scientific conference two years ago, recovery-oriented critics of radical harm reductionism were not given any platforms, with the exception of one minor presentation on safer supply diversion. Their beliefs seemed clandestine and iconoclastic, despite seemingly having wide buy-in from the addiction medicine community.
While vigorous criticism of harm reductionism was not a major feature of this year’s conference, there was open recognition that legitimate opposition to the movement existed. One major presentation, given by Dr. Didier Jutras-Aswad, explicitly cited safer supply and involuntary treatment as two foci of contention, and encouraged harm reductionists and recovery-oriented experts to grab coffee with one another so that they might foster some sense of mutual understanding.2
Is this change enough?
While CSAM should be commended for encouraging cross-ideological dialogue, its efforts, in this respect, were also superficial and vague. They chose to play it safe, and much was left unsaid and unexplored.
Two addiction medicine doctors I spoke with at the conference—both of whom were critics of safer supply and asked for anonymity—were nonplussed. “You can feel the tension in the air,” said one, who likened the conference to an awkward family dinner where everyone has tacitly agreed to ignore a recent feud. “Reconciliation requires truth,” said the other.
One could also argue that the organization has taken an inconsistent approach to encouraging respectful dialogue. When recovery-oriented experts were being bullied for their views a few years ago, they were largely left on their own. Now that their side is ascendant, and harm reductionists are politically vulnerable, mutual respect is in fashion again.
When I asked to interview the organization about navigating dissension, they sent a short, unspecific statement that emphasized “evidence-based practices” and the “benefits of exploring a variety of viewpoints, and the need to constantly challenge or re-evaluate our own positions based on the available science.”
But one cannot simply appeal to “evidence-based practices” when research is contentious and vulnerable to ideological meddling or misrepresentation.
Compared to other medical disciplines, addiction medicine is highly political. Grappling with larger, non-empirical questions about the role of drug use in society has always necessitated taking a philosophical stance on social norms, and this has been especially true since harm reductionists began emphasizing the structural forces that shape and fuel drug use.
Until Canada’s addiction medicine community facilitates a more robust and open conversation about the politicization of research, and the divided—and inescapably political—nature of their work, the national debate on the overdose crisis will be shambolic. This will have negative downstream impacts on policymaking and, ultimately, people’s lives.
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